Israel Silman Selected Research

5- N,6- O- (N''- octyliminomethylidene)nojirimycin

6/2011

Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.

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Israel Silman Research Topics

Disease

10	Gaucher Disease (Gaucher's Disease) 10/2011 - 07/2003
6	Alzheimer Disease (Alzheimer's Disease) 05/2020 - 01/2003
3	Atherosclerosis 09/2007 - 01/2004
3	Colonic Neoplasms (Colon Cancer) 12/2005 - 06/2005
2	Neoplasms (Cancer) 01/2018 - 12/2005
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2010 - 07/2003
2	Hypersensitivity (Allergy) 04/2005 - 11/2004
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2021
1	Myasthenia Gravis 03/2018
1	Atrophy 01/2017
1	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 01/2017
1	Nervous System Diseases (Neurological Disorders) 09/2010
1	Pain (Aches) 12/2009
1	Poisoning 12/2009
1	Rupture 09/2003

Drug/Important Bio-Agent (IBA)

9	EnzymesIBA 01/2012 - 07/2003
9	Glucosylceramidase (Glucocerebrosidase)IBA 10/2011 - 07/2003
5	Pharmaceutical PreparationsIBA 03/2018 - 01/2003
4	AcetylcholinesteraseIBA 05/2020 - 01/2003
3	Cholinesterase Inhibitors (Anticholinesterases)IBA 03/2018 - 01/2003
3	imiglucerase FDA Link 11/2008 - 12/2006
3	ProdrugsIBA 12/2005 - 06/2005
2	Cholinergic Agents (Cholinergics)IBA 01/2021 - 12/2005
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2012
2	OrganophosphatesIBA 12/2009 - 01/2004
2	Polysaccharides (Glycans)IBA 11/2008 - 09/2007
2	HDL LipoproteinsIBA 09/2007 - 05/2004
2	CholesterolIBA 09/2007 - 05/2004
2	CamptothecinIBA 12/2005 - 06/2005
2	Irinotecan (Camptosar)FDA LinkGeneric 12/2005 - 12/2005
1	Phosphotransferases (Kinase)IBA 04/2019
1	Cholinesterases (Cholinesterase)IBA 04/2019
1	LigandsIBA 01/2019
1	PolyphenolsIBA 03/2018
1	quinolineIBA 03/2018
1	6-chlorotacrineIBA 03/2018
1	huprine YIBA 03/2018
1	ButyrylcholinesteraseIBA 03/2018
1	NitrogenIBA 03/2018
1	Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric 03/2018
1	Tacrine (Cognex)FDA Link 03/2018
1	TriazolesIBA 03/2018
1	hypericinIBA 01/2018
1	Photosensitizing Agents (Photosensitizers)IBA 01/2018
1	CollagenIBA 01/2017
1	Amyloid (Amyloid Fibrils)IBA 01/2012
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2012
1	Peptide Hydrolases (Proteases)FDA Link 01/2012
1	Peptides (Polypeptides)IBA 01/2012
1	GlucosidasesIBA 10/2011
1	AcidsIBA 10/2011
1	5- N,6- O- (N''- octyliminomethylidene)nojirimycinIBA 06/2011
1	nojirimycinIBA 06/2011
1	HydrolasesIBA 12/2010
1	Serine (L-Serine)FDA Link 12/2009
1	SomanIBA 12/2009
1	pralidoxime (Protopam Chloride)FDA Link 12/2009
1	miglustat (Zavesca)FDA Link 09/2007
1	Glucosylceramides (Glucocerebrosides)IBA 09/2007
1	Mannose (D-Mannose)IBA 09/2007
1	Biological ProductsIBA 09/2007
1	Mannose ReceptorIBA 09/2007
1	PoisonsIBA 12/2005
1	Atropine FDA LinkGeneric 12/2005
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 12/2005
1	SolutionsIBA 09/2003
1	LubricantsIBA 09/2003

Therapy/Procedure

4	Enzyme Replacement Therapy 01/2010 - 12/2006
2	Therapeutics 12/2010 - 11/2008
1	Photochemotherapy (Photodynamic Therapy) 01/2018
1	Intravenous Injections 11/2008